Elastosis perforans serpiginosa may be distinguished morphologically and histologically from new cutaneous diseases.
Elastosis perforans serpiginosa (EPS) is an uncommon rind disease in which irregular springy tissue fibers, new connective tissue elements, and cellular rubble are expelled from the papillary dermis through the epidermis. Elastosis perforans serpiginosa is caused by several distinct things. It may be caused by a genetic abnormality or a side effect of medication. Elastic fibers are perceived by the skin to be abnormal and become the primary objects of an inflammatory attack. They may be abnormal as a result of genetic influence or penicillamine. Elastosis perforans serpiginosa is also called Lutz miescher’s syndrome. Perforating diseases that may occur in conjunction with EPS include reactive perforating collagenosis, perforating folliculitis, and kyrle disease. The exect cause of abnormal elastic tissue is unknown but may be from a genetic mutation or external factors such as penicillamine.